Appetite and weight
See everything for appetite and weight →Losing weight and keeping it off.
4ExerciseWidely recommended · Free, for almost everyoneExercise is anything that gets your body moving.4GLP-1 drugsWidely recommended · PrescriptionGLP-1 drugs are a class of medicines used to treat type 2 diabetes by lowering blood sugar, and some are used for weight loss in people with obesity.4MetforminWidely recommended · Prescription, approved for diabetesMetformin belongs to a class of drugs called biguanides.3Calorie restriction and fastingLarge studies in people · Free; a change in eatingCalorie restriction means eating fewer calories than usual without missing key nutrients, while fasting diets limit when or how much a person eats.3BerberineLarge studies in people · Over-the-counter supplementBerberine is a substance found in several plants, such as goldenseal, barberry, and Oregon grape.3Testosterone therapyLarge studies in people · PrescriptionTestosterone therapy uses man-made testosterone to treat low testosterone, and it can be given as a pill, gel, patch, injection, or implant.
Metabolism
See everything for metabolism →How the body uses energy and handles sugar and fat.
3BerberineLarge studies in people · Over-the-counter supplementBerberine is a substance found in several plants, such as goldenseal, barberry, and Oregon grape.3Testosterone therapyLarge studies in people · PrescriptionTestosterone therapy uses man-made testosterone to treat low testosterone, and it can be given as a pill, gel, patch, injection, or implant.
Recent research
Tiny particles and microRNAs may link exercise to brain aging
This review looks at small molecules carried in body fluids that may help exercise affect the aging brain.
Small pilot tests drug and digital tracking for healthy aging in older adults
A small study gave 31 adults in Israel one of two drug mixes for about eight weeks and tracked them with phone-based checks.
Study compares muscle tiredness in younger and older adults and tests strength training
Researchers plan to compare younger and older adults to learn why leg muscles tire faster with age.
Can light weight training with blood flow limits help colon cancer survivors with muscle loss?
This is a trial plan that has not reported results yet.
Also see: Age reversal, what the research really shows →
Books on this
This is general information gathered from the sources listed, not medical advice. Talk to your doctor before starting anything new.