Saturday, October 17, 2026 · Edition updated 6:00 AM ETSAT, OCT 17 · 6 AM ET editionNext edition in Next --:--:--

Chemical peels

An acid solution applied to the face that removes the outer layers of skin, so smoother new skin grows back. Peels range from light to deep.

How people get it: Done by dermatologists and med spas. Light peels are also sold for home use.

The basics

What it is

Chemical peels are also called chemexfoliation or derma peeling. Peel products contain acids such as TCA, glycolic acid, salicylic acid and lactic acid.

Sources: American Academy of Dermatology: Chemical peels: Overview ↗ · FDA: FDA warns against purchasing or using chemical peel skin products without professional supervision ↗

How it's thought to work

Peel products remove layers of skin to different depths. The strength of the acid, number of applications, and time left on the skin all affect how deeply a peel goes.

Source: FDA: FDA warns against purchasing or using chemical peel skin products without professional supervision ↗

What people use it for

Dermatologists use peels to treat some types of acne and conditions that discolor the skin. Peel products are marketed for acne, discoloration, wrinkles, and collagen production.

Sources: American Academy of Dermatology: Chemical peels: Overview ↗ · FDA: FDA warns against purchasing or using chemical peel skin products without professional supervision ↗

What the research has found so far

On Chemical peels and aging, PubMed lists 47 trials in people, 46 studies that watched people over time, 9 animal and lab studies. See the counts and searches

2
Research stage 2 of 4 · Small studies in people

Stage 2 because there are 47 published trials and 20 registered trials in people, but no large ones yet.

A stage shows how far research has got, not whether it will work for you. How stages work

Side effects and risks

The FDA says peel products may cause severe chemical burns, pain, swelling, infection, skin color changes, and disfiguring scars. The FDA says these injuries may even need emergency care or care from a dermatologist or surgeon.

Source: FDA: FDA warns against purchasing or using chemical peel skin products without professional supervision ↗

Who should be careful, and drug interactions

The FDA warns that high-strength acid peel products may lead to serious injury from chemical burns. The FDA says the acid strengths in many products are too high to use safely at home without supervision.

Source: FDA: FDA warns against purchasing or using chemical peel skin products without professional supervision ↗

Approval and legal status

The FDA says it has not approved any chemical peel products. The FDA has sent warning letters to companies selling these products. The FDA says consumers should only consider using peel products under a dermatologist or licensed, trained practitioner.

Source: FDA: FDA warns against purchasing or using chemical peel skin products without professional supervision ↗

Roughly what it costs

We don't have prices for this yet.

Questions to ask your doctor

  • Is Chemical peels a sensible option for me, given my health and the medicines I take?
  • Could Chemical peels interact with any medicine or supplement I already take?
  • What side effects should I watch for, and when should I stop or call you?
  • How would we tell whether it is helping, and when should we review it?

This is general information gathered from the sources listed, not medical advice. Talk to your doctor before starting anything new.

What experts say

No expert views collected yet. Each one we add names the person and links to where they said it.

Recent research

New studies that mention Chemical peels appear here after the morning update.

See all research on Chemical peels →

Trials

None of the registered trials of Chemical peels is one we have linked as aging-related yet.

ClinicalTrials.gov lists 20 registered trials that mention Chemical peels, for any condition (the count in The science below). Here we show the ones about aging. See them all ↗

Find Chemical peels trials near you →

The science

Counted from PubMed and ClinicalTrials.gov on Oct 17, 2026, using one search for Chemical peels in relation to aging. Each link opens the exact search.

Randomized trials in people
29 search ↗
Large trials (multicenter or phase 3)
1 search ↗
Phase 3 trials
0 search ↗
Trials in people
47 search ↗
Studies that watched people over time
46 search ↗
Animal and lab studies
9 search ↗
Registered trials
20 search ↗

PubMed search used

("chemical peel*"[tiab] OR "chemical peeling"[tiab] OR "chemexfoliation"[tiab] OR "glycolic acid peel*"[tiab] OR "trichloroacetic acid peel*"[tiab] OR "TCA peel*"[tiab] OR "salicylic acid peel*"[tiab] OR "phenol peel*"[tiab] OR "Jessner"[tiab]) AND (wrinkle*[tiab] OR rejuvenation[tiab] OR "sun damage"[tiab] OR lentig*[tiab] OR photoaging[tiab] OR "skin aging"[tiab] OR "skin ageing"[tiab] OR photodamage[tiab] OR "Skin Aging"[mh])

Counts are search results, so they include some records that only mention Chemical peels. How we count

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Cite this page (APA)

Longevity Verdict. (n.d.). Chemical peels: Research stage and evidence. Retrieved October 17, 2026, from https://longevityverdict.com/treatments/chemical-peels

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The badge shows this treatment's current research stage and links back here. It updates by itself when the stage changes.

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