How people get it: Used in hospitals for approved uses such as decompression sickness and some wounds. Private clinics also offer it; aging is not an approved use.
The basics
What it is
It uses a special pressure chamber to raise the amount of oxygen in the blood. In a one-person chamber, you lie on a bed that slides into a clear tube.
Sources: MedlinePlus (NIH): Hyperbaric oxygen therapy: MedlinePlus Medical Encyclopedia ↗ · Mayo Clinic: Hyperbaric oxygen therapy - Mayo Clinic ↗
How it's thought to work
Effects on the body include removing trapped air bubbles and helping new blood vessels and tissue grow.
Source: Mayo Clinic: Hyperbaric oxygen therapy - Mayo Clinic ↗
What people use it for
It is used for decompression sickness, a problem caused by rapid pressure drops in scuba diving or air or space travel. It may be used for wounds that have not healed with other treatments, such as a diabetic foot ulcer.
Sources: Mayo Clinic: Hyperbaric oxygen therapy - Mayo Clinic ↗ · MedlinePlus (NIH): Hyperbaric oxygen therapy: MedlinePlus Medical Encyclopedia ↗
What the research has found so far
On Hyperbaric oxygen therapy and aging, PubMed lists 6 trials in people, 6 studies that watched people over time, 48 animal and lab studies. See the counts and searches
Stage 2 because there are 6 published trials and 68 registered trials in people, but no large ones yet.
A stage shows how far research has got, not whether it will work for you. How stages work
Side effects and risks
- You might feel pressure in your ears, and they may pop afterward.
- Increased pressure or pure oxygen can cause ear pain and middle ear injuries, including eardrum rupture and fluid leaking from the middle ear.
- It can cause sinus pressure with pain, runny nose or nose bleeds.
- Cataract formation can occur with long courses of treatment.
- It can cause a short-term decline in lung function.
- People with diabetes treated with insulin may get low blood sugar.
- Some people feel anxiety in an enclosed space.
- After treatment you may feel somewhat tired or hungry.
Sources: MedlinePlus (NIH): Hyperbaric oxygen therapy: MedlinePlus Medical Encyclopedia ↗ · Mayo Clinic: Hyperbaric oxygen therapy - Mayo Clinic ↗
Who should be careful, and drug interactions
- The risk of complications rises with longer and repeated therapies.
- Items such as lighters and battery-powered devices that generate heat are not allowed in the chamber.
- People are asked not to wear or use hair or skin care products such as lip balm, lotion, makeup or hair spray.
Source: Mayo Clinic: Hyperbaric oxygen therapy - Mayo Clinic ↗
What studies and labels describe
What studies or labels describe, not a recommendation.
- The air pressure in the chamber is increased to 2 to 3 times normal air pressure.
- For most conditions, a session lasts 1 1/2 to 2 hours.
- Long-term conditions may be treated over days or weeks.
Sources: Mayo Clinic: Hyperbaric oxygen therapy - Mayo Clinic ↗ · MedlinePlus (NIH): Hyperbaric oxygen therapy: MedlinePlus Medical Encyclopedia ↗
Roughly what it costs
We don't have prices for this yet.
Questions to ask your doctor
- Is Hyperbaric oxygen therapy a sensible option for me, given my health and the medicines I take?
- Could Hyperbaric oxygen therapy interact with any medicine or supplement I already take?
- What side effects should I watch for, and when should I stop or call you?
- How would we tell whether it is helping, and when should we review it?
This is general information gathered from the sources listed, not medical advice. Talk to your doctor before starting anything new.
What experts say
No expert views collected yet. Each one we add names the person and links to where they said it.
Recent research
New studies that mention Hyperbaric oxygen therapy appear here after the morning update.
Trials
None of the registered trials of Hyperbaric oxygen therapy is one we have linked as aging-related yet.
ClinicalTrials.gov lists 68 registered trials that mention Hyperbaric oxygen therapy, for any condition (the count in The science below). Here we show the ones about aging. See them all ↗
The science
Counted from PubMed and ClinicalTrials.gov on Oct 17, 2026, using one search for Hyperbaric oxygen therapy in relation to aging. Each link opens the exact search.
- Randomized trials in people
- 3 search ↗
- Large trials (multicenter or phase 3)
- 0 search ↗
- Phase 3 trials
- 0 search ↗
- Trials in people
- 6 search ↗
- Studies that watched people over time
- 6 search ↗
- Animal and lab studies
- 48 search ↗
- Registered trials
- 68 search ↗
PubMed search used
("hyperbaric oxygen"[tiab] OR "Hyperbaric Oxygenation"[mh]) AND (aging[tiab] OR ageing[tiab] OR longevity[tiab] OR lifespan[tiab] OR "life span"[tiab] OR healthspan[tiab] OR "Aging"[mh] OR "Longevity"[mh])
Counts are search results, so they include some records that only mention Hyperbaric oxygen therapy. How we count
Cite or share this page
Longevity Verdict. (n.d.). Hyperbaric oxygen therapy: Research stage and evidence. Retrieved October 17, 2026, from https://longevityverdict.com/treatments/hyperbaric-oxygen
<iframe src="https://longevityverdict.com/embed/stage/hyperbaric-oxygen" title="Hyperbaric oxygen therapy: research stage on Longevity Verdict" width="340" height="72" style="border:0" loading="lazy"></iframe>
The badge shows this treatment's current research stage and links back here. It updates by itself when the stage changes.
