How people get it: Done by dermatologists, plastic surgeons and med spas, often over several sessions.
The basics
What it is
- It is usually used on the face, and it cannot fix sagging skin.
- Ablative lasers include CO2 lasers, erbium lasers and combination systems.
- A fractional laser treats the skin in tiny columns.
How it's thought to work
An ablative laser destroys the outer skin layer and heats the skin below, which stimulates collagen, a protein that improves skin firmness and texture. As the wound heals and skin regrows, the treated area is smoother and tighter.
What people use it for
Laser resurfacing is used to treat fine wrinkles, age spots, uneven skin color or texture, sun-damaged skin and mild to moderate acne scars.
What the research has found so far
On Laser resurfacing and aging, PubMed lists 249 trials in people, 327 studies that watched people over time, 62 animal and lab studies. See the counts and searches
Capped at stage 2: the one phase 3 paper this search finds is not a trial of laser resurfacing for skin aging. It tests a numbing cream used during the laser treatment (PubMed 40735955).
A stage shows how far research has got, not whether it will work for you. How stages work
Side effects and risks
- Treated skin may swell, itch or have a burning sensation.
- It can lead to bacterial, viral or fungal infection; the most common is a flare-up of the herpes virus.
- Treated skin can become darker or lighter than before.
- Ablative laser resurfacing carries a slightly higher risk of scarring.
- One source lists pain, swelling, bleeding, scarring, crusting, discoloration and infection as possible risks.
Sources: Mayo Clinic: Laser resurfacing - Mayo Clinic ↗ · American Society for Dermatologic Surgery: Laser Resurfacing for Aging Skin ↗
Who should be careful, and drug interactions
- People with brown or Black skin have a higher risk of long-term skin color changes.
- People may be cautioned against it if they took isotretinoin in the past year.
- People with a connective tissue or autoimmune disease or a weak immune system may be cautioned against it.
- People with a history of keloid scars may be cautioned against it.
- People who had radiation therapy to the face may be cautioned against it.
- People who are pregnant or breastfeeding may be cautioned against it.
- People prone to cold sores may be cautioned against it, since the procedure can trigger breakouts.
- One source lists aspirin, ibuprofen and vitamin E as things that can affect blood clotting before surgery.
Sources: Mayo Clinic: Laser resurfacing - Mayo Clinic ↗ · American Society for Dermatologic Surgery: Laser Resurfacing for Aging Skin ↗
What to expect: sessions, results and recovery
- Ablative resurfacing typically takes 30 minutes to two hours.
- Without a fractional laser, ablative treatment usually needs only one session.
- After ablative treatment, new skin usually covers the area in 7 to 10 days, and full recovery takes at least a month.
- Recovery after nonablative treatment is very short.
- One source gives recovery of generally up to two weeks for CO2 laser and one full week for erbium laser.
- Healing typically takes 10 to 21 days, depending on the size and location of the procedure.
- The effect may last for years.
Sources: Mayo Clinic: Laser resurfacing - Mayo Clinic ↗ · American Society of Plastic Surgeons: Laser Skin Resurfacing Recovery ↗ · American Society for Dermatologic Surgery: Laser Resurfacing for Aging Skin ↗
Roughly what it costs
We don't have prices for this yet.
Questions to ask your doctor
- Is Laser resurfacing a sensible option for me, given my health and the medicines I take?
- Could Laser resurfacing interact with any medicine or supplement I already take?
- What side effects should I watch for, and when should I stop or call you?
- How would we tell whether it is helping, and when should we review it?
This is general information gathered from the sources listed, not medical advice. Talk to your doctor before starting anything new.
What experts say
No expert views collected yet. Each one we add names the person and links to where they said it.
Recent research
New studies that mention Laser resurfacing appear here after the morning update.
Trials
None of the registered trials of Laser resurfacing is one we have linked as aging-related yet.
ClinicalTrials.gov lists 70 registered trials that mention Laser resurfacing, for any condition (the count in The science below). Here we show the ones about aging. See them all ↗
The science
Counted from PubMed and ClinicalTrials.gov on Oct 17, 2026, using one search for Laser resurfacing in relation to aging. Each link opens the exact search.
- Randomized trials in people
- 157 search ↗
- Large trials (multicenter or phase 3)
- 7 search ↗
- Phase 3 trials
- 1 search ↗
- Trials in people
- 249 search ↗
- Studies that watched people over time
- 327 search ↗
- Animal and lab studies
- 62 search ↗
- Registered trials
- 70 search ↗
PubMed search used
("laser resurfacing"[tiab] OR "fractional laser*"[tiab] OR "fractional CO2"[tiab] OR "fractional carbon dioxide"[tiab] OR "CO2 laser*"[tiab] OR "carbon dioxide laser*"[tiab] OR "erbium:YAG"[tiab] OR "Er:YAG"[tiab] OR "fractional photothermolysis"[tiab] OR "ablative laser*"[tiab] OR "non-ablative laser*"[tiab] OR "nonablative laser*"[tiab] OR "picosecond laser*"[tiab]) AND (wrinkle*[tiab] OR rhytid*[tiab] OR rejuvenation[tiab] OR "sun damage"[tiab] OR photoaging[tiab] OR "skin aging"[tiab] OR "skin ageing"[tiab] OR photodamage[tiab] OR "Skin Aging"[mh])
Counts are search results, so they include some records that only mention Laser resurfacing. How we count
Cite or share this page
Longevity Verdict. (n.d.). Laser resurfacing (CO2 and fractional lasers): Research stage and evidence. Retrieved October 17, 2026, from https://longevityverdict.com/treatments/laser-resurfacing
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The badge shows this treatment's current research stage and links back here. It updates by itself when the stage changes.
