Saturday, October 17, 2026 · Edition updated 6:00 AM ETSAT, OCT 17 · 6 AM ET editionNext edition in Next --:--:--

NMN (nicotinamide mononucleotide)

A molecule the body uses to make NAD+, which cells need to turn food into energy.

How people get it: Sold as a supplement in capsules and powders.

Part of Age reversal: drugs and supplements studied for slowing aging

The basics

What the research has found so far

A review of studies found that effects of NMN and a related compound on health outcomes were mixed and often null. The same review said whether NAD+ boosting works for anti-aging or wellness remains unclear.

Source: PubMed abstract: pubmed.ncbi.nlm.nih.gov ↗

On NMN and aging, PubMed lists 9 trials in people, 0 studies that watched people over time, 134 animal and lab studies. See the counts and searches

2
Research stage 2 of 4 · Small studies in people

Stage 2 because there are 9 published trials and 55 registered trials in people, but no large ones yet.

A stage shows how far research has got, not whether it will work for you. How stages work

Side effects and risks

A review of studies found that oral NMN and NR (a related compound) were generally well tolerated over weeks to months in people.

Source: PubMed abstract: pubmed.ncbi.nlm.nih.gov ↗

Approval and legal status

The FDA now concludes that NMN is not excluded from being sold as a dietary supplement, after revising how it reads the law.

Source: FDA (regulations.gov): Response to citizen petition FDA-2023-P-0872, signed 29 September 2025 ↗

Amounts used in studies

What studies or labels describe, not a recommendation.

A review of eight trials found studies used NMN at 250 to 2000 mg per day for 14 days to 12 weeks.

Source: PubMed abstract: pubmed.ncbi.nlm.nih.gov ↗

Roughly what it costs

The 14 products we list that contain NMN cost from $14.96 to $118, as read from the makers' pages. See the products

Questions to ask your doctor

  • Is NMN a sensible option for me, given my health and the medicines I take?
  • Could NMN interact with any medicine or supplement I already take?
  • What side effects should I watch for, and when should I stop or call you?
  • Supplements aren't checked by the FDA before sale. Is there a brand or a third-party test seal you would trust?
  • How would we tell whether it is helping, and when should we review it?

This is general information gathered from the sources listed, not medical advice. Talk to your doctor before starting anything new.

Products that contain it

Read from each maker's page. The research stage is for the ingredient, not proof that a product works.

Sort by
ProductFormNMN per servingPricePer serving
Essentials NMN 300 - Nexergy™ NMN - 300 mg, 30 capsulesProHealth Longevity · maker's page ↗capsule300 mgserving: 1 Capsule$14.9630 servings$0.50
Essentials NMN Powder - Nexergy™ NMN - 100 gramsProHealth Longevity · maker's page ↗powder1000 mgserving: 1 Scoop$59.96100 servings$0.60
Essentials NMN 500 - Nexergy™ NMN - 500 mg, 30 capsulesProHealth Longevity · maker's page ↗capsule500 mgserving: 1 Capsule$24.9530 servings$0.83
NMNR™ Pro Synergy - 90 capsulesProHealth Longevity · maker's page ↗capsule500 mgserving: 3 Capsules$35.9530 servings$1.20
Essentials NMN 1000 - Nexergy™ NMN - 1000 mg per serving, 60 capsulesProHealth Longevity · maker's page ↗capsule1000 mgserving: 2 Capsules$39.9530 servings$1.33
Liposomal NMN Pro Complete™ - Lipo Uthever® NMN, Trans-Resveratrol, TMG, 90 capsulesProHealth Longevity · maker's page ↗capsule500 mgserving: 3 Capsules$55.9530 servings$1.87
NMN Pro Complete™ - Uthever® NMN, Trans-Resveratrol, TMG - 75 gramsProHealth Longevity · maker's page ↗—1000 mgserving: 1 Scoop (2.5 g)$82.9530 servings$2.77
NMN Pure PowderRenue By Science · maker's page ↗powder500 mg$54.95—
NMNs Fast Dissolve TabsRenue By Science · maker's page ↗tabletSee label$54.95—
NMN SLC Enteric Capsules 200Renue By Science · maker's page ↗capsuleSee label$58.95—
NMN Liposomal CapsulesRenue By Science · maker's page ↗capsule500mg$64.95—
Pure NMN SupplementDoNotAge · maker's page ↗powderSee label$80.00—
NAD+ Powder Supplement With NMNJinfiniti · maker's page ↗powder500mgserving: 1 level scoop, 62 servings per container$118.00—
Sublingual NMN Lozenge: Chewable NAD+ BoosterJinfiniti · maker's page ↗lozenge500mgserving: 1 Tablet, 62 servings per container$118.00—

Amounts, servings and prices are as each maker lists them on its own page, checked Oct 16, 2026. Price per serving is the price divided by the servings per container on the label; “—” means the page didn't say. A serving is the maker's serving size, not a recommendation.

What experts say

“But it’s premature to make any clinical recommendations based on the results from our study. NMN needs to be tested in more people and for longer periods of time to determine if it has anti-ageing effects in humans,”

Samuel Klein, doctor and nutritional specialist at Washington University School of Medicine in St Louis, United States · Nature · Source ↗

“Finding an effect in muscle tissue is very interesting and does demonstrate that NMN is not inert,”

Samuel Klein, doctor and nutritional specialist at Washington University School of Medicine in St Louis, United States · Nature · Source ↗

“It mightn’t be wise to increase cellular entry of NMN, as an increased intracellular NMN/NAD + ratio activates SARM1, an executor of axon degeneration.”

Evandro Fei Fang, molecular gerontologist leading an anti-ageing laboratory at the University of Oslo, Norway · Nature · Source ↗
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Recent research

New studies that mention NMN appear here after the morning update.

See all research on NMN →

Trials

None of the registered trials of NMN is one we have linked as aging-related yet.

ClinicalTrials.gov lists 55 registered trials that mention NMN, for any condition (the count in The science below). Here we show the ones about aging. See them all ↗

Find NMN trials near you →

The science

Counted from PubMed and ClinicalTrials.gov on Oct 17, 2026, using one search for NMN in relation to aging. Each link opens the exact search.

Randomized trials in people
7 search ↗
Large trials (multicenter or phase 3)
1 search ↗
Phase 3 trials
0 search ↗
Trials in people
9 search ↗
Studies that watched people over time
0 search ↗
Animal and lab studies
134 search ↗
Registered trials
55 search ↗

PubMed search used

("nicotinamide mononucleotide"[tiab] OR NMN[tiab]) AND (aging[tiab] OR ageing[tiab] OR longevity[tiab] OR lifespan[tiab] OR "life span"[tiab] OR healthspan[tiab] OR "Aging"[mh] OR "Longevity"[mh])

Counts are search results, so they include some records that only mention NMN. How we count

Report a problem