Saturday, October 17, 2026 · Edition updated 6:00 AM ETSAT, OCT 17 · 6 AM ET editionNext edition in Next --:--:--

Plasma exchange and young plasma

Replacing part of the liquid part of the blood (plasma), either with a saline and albumin mix or with plasma from young donors.

How people get it: Done in clinics and in clinical trials, using a machine that filters the blood.

Part of Age reversal: plasma exchange and young blood

The basics

We're still gathering this from reference sources like the NIH and MedlinePlus. Sections appear here once every sentence is checked against its source.

What it is

Not enough reliable information yet.

How it's thought to work

Not enough reliable information yet.

What people use it for

Not enough reliable information yet.

What the research has found so far

On Plasma exchange and young plasma and aging, PubMed lists 6 trials in people, 10 studies that watched people over time, 222 animal and lab studies. See the counts and searches

3
Research stage 3 of 4 · Large studies in people

Stage 3 because 2 large (phase 3) trials in people for aging, skin and hair or memory and mood have been published.

A stage shows how far research has got, not whether it will work for you. How stages work

Side effects and risks

Not enough reliable information yet.

Who should be careful, and drug interactions

Not enough reliable information yet.

What to expect: sessions, results and recovery

Not enough reliable information yet.

Roughly what it costs

We don't have prices for this yet.

Questions to ask your doctor

  • Is Plasma exchange and young plasma a sensible option for me, given my health and the medicines I take?
  • Could Plasma exchange and young plasma interact with any medicine or supplement I already take?
  • What side effects should I watch for, and when should I stop or call you?
  • How would we tell whether it is helping, and when should we review it?

This is general information gathered from the sources listed, not medical advice. Talk to your doctor before starting anything new.

What experts say

No expert views collected yet. Each one we add names the person and links to where they said it.

What others are writing

Recent articles about Plasma exchange and young plasma from health journalists, hospitals and universities. We link to them; we don't write or endorse them.

uc.edu · Megan Burgasser · May 28, 2025

Could plasma exchange therapy help you live longer? ↗

“Still, many other scientists who study plasma exchange are skeptical. Its anti-aging benefits for healthy people have not been proven in large clinical trials, and drawing blood and replacing plasma with added fluids could put patients at risk for unnecessary medical complications without a clear payoff.”

A University of Cincinnati expert comments on a small anti-aging plasma exchange trial and notes that many scientists remain skeptical of its benefits.

Recent research

New studies that mention Plasma exchange and young plasma appear here after the morning update.

See all research on Plasma exchange and young plasma →

Trials

None of the registered trials of Plasma exchange and young plasma is one we have linked as aging-related yet.

ClinicalTrials.gov lists 12 registered trials that mention Plasma exchange and young plasma, for any condition (the count in The science below). Here we show the ones about aging. See them all ↗

Find Plasma exchange and young plasma trials near you →

The science

Counted from PubMed and ClinicalTrials.gov on Oct 17, 2026, using one search for Plasma exchange and young plasma in relation to aging. Each link opens the exact search.

Randomized trials in people
4 search ↗
Large trials (multicenter or phase 3)
0 search ↗
Phase 3 trials
0 search ↗
Trials in people
6 search ↗
Studies that watched people over time
10 search ↗
Animal and lab studies
222 search ↗
Registered trials
12 search ↗

PubMed search used

("therapeutic plasma exchange"[tiab] OR "plasma exchange"[tiab] OR "young plasma"[tiab] OR "young blood"[tiab] OR heterochronic[tiab] OR parabiosis[tiab]) AND (aging[tiab] OR ageing[tiab] OR longevity[tiab] OR lifespan[tiab] OR "life span"[tiab] OR healthspan[tiab] OR "Aging"[mh] OR "Longevity"[mh])

Counts are search results, so they include some records that only mention Plasma exchange and young plasma. How we count

Cite or share this page

Cite this page (APA)

Longevity Verdict. (n.d.). Plasma exchange and young plasma: Research stage and evidence. Retrieved October 17, 2026, from https://longevityverdict.com/treatments/plasma-exchange

Embed the research stage on your site

<iframe src="https://longevityverdict.com/embed/stage/plasma-exchange" title="Plasma exchange and young plasma: research stage on Longevity Verdict" width="340" height="72" style="border:0" loading="lazy"></iframe>

The badge shows this treatment's current research stage and links back here. It updates by itself when the stage changes.

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