How people get it: Sold as a supplement, and in some foods and skin products.
Part of Age reversal: drugs and supplements studied for slowing aging
The basics
What it is
Urolithin A is a gut metabolite, a substance made in the gut, derived from ellagic acid.
Source: PubMed abstract: Targeting aging with urolithin A in humans: A systematic review. ↗
What the research has found so far
- A review of studies found urolithin A raised some mitochondrial genes, signs of autophagy, and fatty acid burning. Mitochondria are the cell's energy makers.
- A review of studies found urolithin A showed an anti-inflammatory effect that grew with the dose.
- A review of studies found urolithin A increased muscle strength and endurance in healthy people.
- A review of studies found no effect on body measurements, heart and blood vessel outcomes, or physical function.
- The review says more research over longer periods and across more body systems is needed.
Source: PubMed abstract: Targeting aging with urolithin A in humans: A systematic review. ↗
On Urolithin A and aging, PubMed lists 32 trials in people, 3 studies that watched people over time, 177 animal and lab studies. See the counts and searches
Stage 2 because there are 32 published trials and 43 registered trials in people, but no large ones yet.
A stage shows how far research has got, not whether it will work for you. How stages work
Side effects and risks
A review of studies found that adverse events not related to urolithin A were mild or moderate.
Source: PubMed abstract: Targeting aging with urolithin A in humans: A systematic review. ↗
Amounts used in studies
What studies or labels describe, not a recommendation.
A review of five studies in 250 healthy people found that studies used 10 to 1000 mg a day, for 28 days to 4 months.
Source: PubMed abstract: Targeting aging with urolithin A in humans: A systematic review. ↗
Roughly what it costs
The 7 products we list that contain Urolithin A cost from $10 to $89, as read from the makers' pages. See the products
Questions to ask your doctor
- Is Urolithin A a sensible option for me, given my health and the medicines I take?
- Could Urolithin A interact with any medicine or supplement I already take?
- What side effects should I watch for, and when should I stop or call you?
- Supplements aren't checked by the FDA before sale. Is there a brand or a third-party test seal you would trust?
- How would we tell whether it is helping, and when should we review it?
This is general information gathered from the sources listed, not medical advice. Talk to your doctor before starting anything new.
Products that contain it
Read from each maker's page. The research stage is for the ingredient, not proof that a product works.
| Product | Form | Urolithin A per serving | Price | Per serving |
|---|---|---|---|---|
| Full Spectrum Urolithin A - 60 capsulesProHealth Longevity · maker's page ↗ | capsule | 500 mgserving: 2 Capsules | $79.9530 servings | $2.67 |
| Mitopure Softgels SampleTimeline · maker's page ↗ | softgel | See label | $10.00 | — |
| Mitopure Powder SampleTimeline · maker's page ↗ | powder | See label | $10.00 | — |
| Mitopure Gummies SampleTimeline · maker's page ↗ | gummy | See label | $10.00 | — |
| Mitopure SoftgelsTimeline · maker's page ↗ | softgel | 500mg | $89.00 | — |
| Mitopure PowderTimeline · maker's page ↗ | powder | 500mg | $89.00 | — |
| Mitopure GummiesTimeline · maker's page ↗ | gummy | See label | $89.00 | — |
| Shop Mitopure® Urolithin A SamplesTimeline · maker's page ↗ | gummy | See label | — | — |
Amounts, servings and prices are as each maker lists them on its own page, checked Oct 16, 2026. Price per serving is the price divided by the servings per container on the label; “—” means the page didn't say. A serving is the maker's serving size, not a recommendation.
What experts say
No expert views collected yet. Each one we add names the person and links to where they said it.
Recent research
New studies that mention Urolithin A appear here after the morning update.
Trials
None of the registered trials of Urolithin A is one we have linked as aging-related yet.
ClinicalTrials.gov lists 43 registered trials that mention Urolithin A, for any condition (the count in The science below). Here we show the ones about aging. See them all ↗
The science
Counted from PubMed and ClinicalTrials.gov on Oct 17, 2026, using one search for Urolithin A in relation to aging. Each link opens the exact search.
- Randomized trials in people
- 26 search ↗
- Large trials (multicenter or phase 3)
- 1 search ↗
- Phase 3 trials
- 0 search ↗
- Trials in people
- 32 search ↗
- Studies that watched people over time
- 3 search ↗
- Animal and lab studies
- 177 search ↗
- Registered trials
- 43 search ↗
PubMed search used
"urolithin A"[tiab]
Counts are search results, so they include some records that only mention Urolithin A. How we count