What this means
This is a research study that is still recruiting people, and it has not posted results yet. It will collect blood, urine, scans, and many tests over repeated visits to learn more about aging markers.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 20–120
- Where
- 1 site, including Maryland
The science
- Registered title
- Genetic and Epigenetic Signatures of Translational Aging Laboratory Testing (GESTALT)
- Trial ID
- NCT02339012 ↗
- Phase
- Not applicable
- Study type
- observational
- Conditions
- Healthy Volunteers, Non-Healthy/Non-Frail, Frail
- Sponsor
- National Institute on Aging (NIA)
- Ages
- 20 Years to 120 Years
- Dates
- First posted Jan 15, 2015 · updated Oct 13, 2026
Registry summary
Background:
- Biomarkers are substances in people's blood and tissues. They help researchers understand diseases and signs of aging. Scientists want to do more research on biomarkers to find ways to improve quality of life in old age.
Objective:
- To learn more about biomarkers and their relationship to aging.
Eligibility:
- Adults at least 20 years old who weigh at least 110 pounds and have a body mass index below 30. They must agree that their genetic samples can be collected, studied, and stored.
Design:
- Participants will be screened with medical history, physical exam, EKG and blood and urine tests.
- Participants will have 3-day visits. They will return every 2 years.
- All visits include:
- Blood and urine collection
- Physical performance tests
- Health questionnaires
- Memory and problem-solving tests
- Magnetic Resonance Imaging (MRI) and Computerized Tomography (CT) scans.
- Muscle metabolism/ exercise tests
- Taste strips
- Muscle and/or skin biopsies/ red light therapy
- Retinal imaging/ eye tracking
- Sleep study
- ODD visits also include:
- Cytapheresis
- Bone marrow aspirate
- EVEN visits also include:
- Hyperglycemic CLAMP
- Lumbar Puncture (LP)
- Continuous Glucose Monitor (CGM)
Sites (1)
- National Institute of Aging, Clinical Research Unit, Baltimore, Maryland, United States