What this means
This study plans to take blood, urine, joint fluid, and tissue samples to look for signs of aging cells. It has not reported results, so it does not yet show what the signs mean.
Plain-English summary written by an AI model from the registry listing.
- Status
- Completed
- Who can join
- Ages 35 and over · about 30 people with knee osteoarthritis
- Where
- 1 site, including Maryland
The science
- Registered title
- An Exploratory Clinical Study to Investigate Biomarkers of Senescence in Patients With Osteoarthritis of the Knee
- Trial ID
- NCT03100799 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Osteoarthritis, Knee
- What is tested
- Arthroscopy, Arthrocentesis, MRI
- Sponsor
- Unity Biotechnology, Inc.
- Ages
- 35 Years to no maximum
- Dates
- First posted Apr 4, 2017 · updated Aug 1, 2017
Registry summary
This is an exploratory non-drug, interventional biomarker study in approximately 30 eligible patients with active osteoarthritis to investigate the degree of senescence-associated disease. Patients will provide blood and urine and undergo MRI imaging with and without gadolinium enhancement. Following imaging, arthrocentesis of both knees and an arthroscopy of the target knee will occur to obtain fluid, synovium and cartilage for analysis.
Sites (1)
- The Arthritis Treatment Center, Frederick, Maryland, United States