What this means
Researchers plan to measure frailty in older people with HIV and see how it links to death and quality of life. They will watch participants for 10 years to find what raises frailty risk.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 50 and over
- Where
- 1 site
The science
- Registered title
- Frailty in Older HIV-infected Individuals
- Trial ID
- NCT03413683 ↗
- Phase
- Not applicable
- Study type
- observational
- Conditions
- HIV Infections
- Sponsor
- Chinese University of Hong Kong
- Ages
- 50 Years to no maximum
- Dates
- First posted Jan 29, 2018 · updated Aug 30, 2023
Registry summary
Frailty has been proposed as a measure of biological (as opposed to chronological) aging. In this study the investigators plan to: (1) measure frailty in a cohort of older HIV-infected individuals in Hong Kong, and its association with mortality and quality of life; (2) identify risk factors predictive of development of frailty in HIV-infected individuals in Hong Kong; and (3) determine the outcomes of HIV-infected individuals in Hong Kong with and without frailty.
The following assessment will be done:
- Physical examination including measuring height, weight, hip and waist circumference.
- Grip strength, chair stand test, gait speed test, balance tests, and neurocognitive tests
- Geriatric syndromes, screening for depression, disability and quality of life.
- Blood tests during fasting state to measure metabolic parameters.
This is a prospective longitudinal observational study that lasts for 10 years.
Sites (1)
- Prince of Wales Hospital, Shatin, Hong Kong