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Study will test how stress affects route planning and memory in older adults

Recruiting · Georgia Institute of Technology

What this means

Researchers plan to test whether stress makes people recall fewer details when planning routes. They will also test whether this leads to more habit-based movement. The study has not reported results, so it cannot yet show what happens.

Plain-English summary written by an AI model from the registry listing.

Status
Recruiting
Who can join
Ages 65–80
Where
1 site, including Georgia

Contacts and how to join ↗

The science

Registered title
Neurobiological Mechanisms of Aging and Stress on Prospective Navigation
Phase
Not applicable
Study type
interventional
Conditions
Aging, Anxiety, Memory Impairment
What is tested
Anticipatory psychological stress
Sponsor
Georgia Institute of Technology
Ages
65 Years to 80 Years
Dates
First posted Apr 1, 2019 · updated Sep 23, 2026

Registry summary

Two hallmarks of both healthy aging and age-related disease are 1) memory and navigational deficits, particularly in orienting towards goal locations and planning how to navigate to them, and 2) increased susceptibility to stress and altered regulation of the stress response. However, there are marked individual differences in these age-related changes. The investigators' proposal will help characterize factors that contribute to this variability.

Participants will be pseudorandomly assigned to stress-manipulated or control groups. The investigators will give both groups a novel immersive navigation task, validated by the PI in healthy young adults. This paradigm gives participants the opportunity to either (a) flexibly draw on spatial memory in order to plan efficient routes to goal locations, or (b) fall back on inefficient, but cognitively less-demanding, stimulus-response associations (i.e., habits). Using neuroimaging and behavioral measures, the investigators' protocol will test whether experimentally-induced stress leads individuals to bring fewer details about future locations to mind when route planning, and whether such restricted prospective thought ultimately biases participants towards relatively inflexible, habitual actions.

Sites (1)

  • Center for Advance Brain Imaging, Atlanta, Georgia, United States

More aging trials in these states

Georgia

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