What this means
Researchers will treat one forearm of older adults with laser and leave the other arm untreated. They want to see if fewer sun-damage spots and skin cancers appear later. This is a study that has not reported results yet, so it cannot show whether the laser works.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 60 and over
- Where
- 1 site, including Ohio
The science
- Registered title
- Effectiveness of Fractionated Laser Resurfacing to Protect Geriatric Skin From Actinic Neoplasia
- Trial ID
- NCT03906253 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Actinic Keratoses, Aging, Non-Melanoma Skin Cancer
- What is tested
- Fractionated Laser Resurfacing
- Sponsor
- Wright State University
- Ages
- 60 Years to no maximum
- Dates
- First posted Apr 8, 2019 · updated Jul 17, 2026
Registry summary
This study is following up on previous studies that have demonstrated that geriatric subjects respond different to ultraviolet B (UVB) light than young subjects. The treatment of geriatric skin with dermal rejuvenation therapies (dermabrasion, fractionated laser resurfacing) restores the appropriate UVB response. Ongoing studies have tested the ability of fractionated laser resurfacing (FLR) to assess how long this wounding effect lasts-and have found that this appears to be a durable response which lasts for at least two years. The findings that FLR protects geriatric skin at two years is the impetus for this study.
This study is an interventional study to assess if FLR treatment of one forearm of geriatric subjects with multiple actinic keratosis will result in the short-term removal of actinic keratosis, and the long-term decrease in levels of future actinic keratosis and other non-melanoma skin cancers in comparison to the untreated arm.
Study length and visit: The first part of the study is completed in 1 day then there are follow up visits at 90 days and every 6 months for 5 years.
Sites (1)
- Dayton VA Medical Center, Dayton, Ohio, United States