What this means
The study looked at how the drug moves in the body, its safety, and how long it lasts after one injection into the eye. It does not show whether the drug helps vision or is right for anyone.
Plain-English summary written by an AI model from the registry listing.
- Status
- Completed
- Who can join
- Ages 18 and over
- Where
- 22 sites, including Arizona, California, Colorado
The science
- Registered title
- Safety, Tolerability and Evidence of Activity Study of UBX1325 in Patients With Diabetic Macular Edema (BEHOLD)
- Trial ID
- NCT04857996 ↗
- Phase
- PHASE 2
- Study type
- interventional
- Conditions
- Diabetic Macular Edema (DME)
- What is tested
- UBX1325, Sham
- Sponsor
- Unity Biotechnology, Inc.
- Ages
- 18 Years to no maximum
- Dates
- First posted Apr 23, 2021 · updated May 16, 2024
Registry summary
This study is intended to assess the exposure, safety, biological activity, and durability of UBX1325, a phosphate pro-drug, and its active parent molecule (UBX0601) following a single intravitreal (IVT) injection of UBX1325 in patients with diabetic macular edema (DME).
Sites (22)
- Retinal Research Institute, LLC, Phoenix, Arizona, United States
- California Retina Consultants, Bakersfield, California, United States
- The Retina Partners, Encino, California, United States
- Salehi Retina Institute Inc., Huntington Beach, California, United States
- Loma Linda University, Loma Linda, California, United States
- California Retina Consultants, Oxnard, California, United States
- Advanced Vision Research Institute, Longmont, Colorado, United States
- Bascom Palmer Eye Institute, Miami, Florida, United States
- MedEye Associates, Miami, Florida, United States
- Northwestern Medical Group, Chicago, Illinois, United States
- MidWest Eye Institute, Indianapolis, Indiana, United States
- Cumberland Valley Retina Consultants, Hagerstown, Maryland, United States
- Mass Eye and Ear Institute, Boston, Massachusetts, United States
- Sierra Eye Associates, Reno, Nevada, United States
- New York Eye and Ear Infirmary, New York, New York, United States
And 7 more on the listing.
More aging trials in these states
Arizona · California · Colorado · Florida · Illinois · Indiana · Maryland · Massachusetts · Nevada · New York · Oregon · South Carolina · Texas