What this means
This is a plan for a study that has not reported results yet. It will test whether nicotine gum can reverse hearing-related effects of aging.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 18–85
- Where
- 1 site, including California
The science
- Registered title
- Using Nicotine to Reverse Age-related Auditory Processing Deficits
- Trial ID
- NCT04971954 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Auditory Perceptual Impairment, Aging
- What is tested
- Nicotine gum, Placebo gum
- Sponsor
- University of California, Irvine
- Ages
- 18 Years to 85 Years
- Dates
- First posted Jul 22, 2021 · updated Aug 10, 2026
Registry summary
The present study will evaluate the effects of both aging and nicotine on psychophysical tasks and electrophysiological measures. Nicotine will be administered to study participants in the form of gum that is available as an over-the-counter medication. The hypothesis is that nicotine will reverse the detrimental effects of aging on auditory processing. The proposed experiments will characterize the effects of nicotine and may eventually lead to improved treatments of hearing loss in a variety of patient populations and in healthy aging.
Sites (1)
- Hearing and Speech Lab, Irvine, California, United States