What this means
This study will compare how the body's immune system responds to two flu vaccines. It will look at immune, gene, and chemical signals. Recruiting is still open, and no results have been posted yet.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 21 and over
- Where
- 1 site, including Connecticut
The science
- Registered title
- Systems Investigation of Vaccine Responses in Aging and Frailty
- Trial ID
- NCT05291676 ↗
- Phase
- PHASE 2
- Study type
- interventional
- Conditions
- Influenza
- What is tested
- Fluzone, Fluad
- Sponsor
- Yale University
- Ages
- 21 Years to no maximum
- Dates
- First posted Mar 23, 2022 · updated Jun 12, 2025
Registry summary
This study will compare the immune response signatures (including immunologic, transcriptomic and metabolomic) of the two influenza vaccines approved for use in adults age 65 and over (Fluad and Fluzone High-Dose).
Sites (1)
- Yale School of Medicine, New Haven, Connecticut, United States