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How long dialysis filters last in very sick patients with kidney injury

Recruiting · University Hospital Muenster

What this means

This trial is looking at how long filters last during continuous dialysis in intensive care. It has not posted results yet, so it cannot tell us the answer.

Plain-English summary written by an AI model from the registry listing.

Status
Recruiting
Who can join
Ages 18 and over
Where
5 sites

Contacts and how to join ↗

The science

Registered title
Filter Lifespan in Continuous Renal Replacement Therapy
Phase
Not applicable
Study type
observational
Conditions
Critically Ill, Continuous Renal Replacement Therapy, Infections
What is tested
Critically ill patients with continuous renal replacement therapy
Sponsor
University Hospital Muenster
Ages
18 Years to no maximum
Dates
First posted Jul 8, 2022 · updated Dec 12, 2024

Registry summary

The only supportive therapy for patients with AKI is renal replacement therapy (RRT). In the ICU setting, continuous RRT (CRRT) is mostly favored. In a post-hoc analysis of the RICH trial (regional citrate versus systemic heparin anticoagulation for CRRT in critically ill patient with AKI), it was shown that the filter life span is associated with an increased rate of new infection and that the type of anticoagulants did not directly affect infection rate. The mechanisms of this infection rate is unknown.

Sites (5)

  • Univ.-Klinik Innsbruck, Innsbruck, Austria
  • Universidade de São Paulo, São Paulo, Brazil
  • Universitätsklinikum Erlangen-Nürnberg, Abteilung für Nephrologie und Hypertensiologie, Erlangen, Germany
  • Kliniken Maria Hilf, Klinik für Anästhesiologie und Operative Intensivmedizin, Mönchengladbach, Germany
  • University Hospital Muenster, Münster, Germany
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