What this means
This study will compare dance-based cardio exercise with a strength, flexibility, and balance program. It will check effects on memory-related thinking and brain scans. Results are not yet known, so it cannot show which exercise helps.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 60 and over
- Where
- 1 site, including New Jersey
The science
- Registered title
- Exercise to Improve Brain Health in Older African Americans
- Trial ID
- NCT05597124 ↗
- Phase
- PHASE 2
- Study type
- interventional
- Conditions
- Aging, Alzheimer Disease, Healthy Aging, Cognitive Change
- What is tested
- Cardio-Dance Fitness, Strength, Flexibility & Balance
- Sponsor
- Rutgers, The State University of New Jersey
- Ages
- 60 Years to no maximum
- Dates
- First posted Oct 27, 2022 · updated Feb 20, 2026
Registry summary
The goal of this clinical trial is to test the effects of different types of exercise on brain health and Alzheimer's risk in older African Americans.
Specifically, the main question[s] it aims to answer are:
- What is the effect of a Cardio-Dance Fitness (CDF) vs. a Strength, Flexibility, and Balance (SFB) intervention on a cognitive marker of Alzheimer's risk, generalization?
- What is the effect of the CDF vs. SFB intervention on a fMRI biomarker of Alzheimer's, neural flexibility, and do improvements in neural flexibility mediate improvements in generalization?
- Do ABCA7 genotypic variations moderate the efficacy of the CDF vs. SFB intervention for reducing Alzheimer's risk?
Participants will undergo-- at baseline and post-test-- health assessments, cognitive tests, and structural and functional magnetic resonance imaging (fMRI), and a blood-draw to assess Alzheimer's risk biomarker levels.
Sites (1)
- Rutgers, The State University of New Jersey - Newark campus, Newark, New Jersey, United States