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Testing whether a low dose of esmolol protects the heart in frail older surgery patients

Recruiting · PHASE 4 · Yongtao Sun

What this means

This is a trial that is still recruiting people, and no results have been posted yet. It will look at heart injury after non-surgery operations, not heart surgery.

Plain-English summary written by an AI model from the registry listing.

Status
Recruiting
Who can join
Ages 65–90
Where
1 site

Contacts and how to join ↗

The science

Registered title
Effects of Low-dose Esmolol on Myocardial Injury After Non-cardiac Surgery in Elderly Frail Patients
Phase
PHASE 4
Study type
interventional
Conditions
Frailty, Esmolol, Myocardial Injury
What is tested
Esmolol, Placebo Comparator: Placebo Comparator:normal saline(0.9%)
Sponsor
Yongtao Sun
Ages
65 Years to 90 Years
Dates
First posted Dec 2, 2022 · updated Mar 29, 2023

Registry summary

This topic will focus on the following questions:

  • Part one: To clarify the relationship between preoperative frailty and myocardial injury (cTnT ≥0.03) after non-cardiac surgery in elderly patients; To further explore the predictive factors of myocardial injury after non-cardiac surgery (MINS) in elderly frail patients before operation.
  • Part Two: To explore the effect of low-dose esmolol on myocardial injury after non-cardiac surgery in frail elderly patients.

Sites (1)

  • Qianfoshan Hospital, The First Hospital affiliated of Shandong First Medical University, Jinan, Shandong, China
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