What this means
Researchers plan to follow 2,000 people aged 60 and over for memory and thinking changes. This is a registration; it has not started recruiting, so no results exist yet.
Plain-English summary written by an AI model from the registry listing.
- Status
- Opening soon
- Who can join
- Ages 60 and over · 2,000 adults aged 60 and over in Shanghai
- Where
- 1 site
The science
- Registered title
- Cognitive Impairment Cohort Study of the Elderly Population in SheMountain
- Trial ID
- NCT05667935 ↗
- Phase
- Not applicable
- Study type
- observational
- Conditions
- Alzheimer Disease, Dementia, Neurodegenerative Diseases, Cognitive Impairment, Mild Cognitive Impairment
- Sponsor
- Ruijin Hospital
- Ages
- 60 Years to no maximum
- Dates
- First posted Dec 29, 2022 · updated Dec 29, 2022
Registry summary
This study is a prospective observational study, which involves a cohort of 2000 all-sex and all-ethnic people aged 60 years and above with permanent residence in Tianma area, SheMountain Town, Songjiang District (suburban area), Shanghai. Demographic information, neuropsychiatric scale, peripheral blood, APOE genotype, brain MRI, speech information, AV45-PET, FDG-PET, Tau-PET, GLP-1R PET, and cholinergic receptor probe (ASEM) PET were collected and analyzed. Follow-up visits were performed twice a year for 4 visits, and neuropsychiatric scales and biological samples were collected at each follow-up visit to construct a diagnostic model for patients with mild cognitive impairment, or Alzheimer's disease, as well as a predictive model for the progression of cognitive impairment.
Sites (1)
- Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, Shanghai Municipality, China