Saturday, October 17, 2026 · Edition updated 6:00 AM ETSAT, OCT 17 · 6 AM ET editionNext edition in Next --:--:--

A gentler surgery for small colon cancers in frail older adults

Recruiting · Zealand University Hospital

What this means

This study is a trial that has not reported results yet, so no outcomes are known. It plans to compare a smaller, gentler surgery with standard surgery to see which helps recovery more.

Plain-English summary written by an AI model from the registry listing.

Status
Recruiting
Who can join
Ages 65 and over
Where
3 sites

Contacts and how to join ↗

The science

Registered title
The "SPARCOL" Study
Phase
Not applicable
Study type
interventional
Conditions
Colon Cancer, Frailty
What is tested
Combined Endoscopic Laparoscopic Surgery (CELS), Standard resection
Sponsor
Zealand University Hospital
Ages
65 Years to no maximum
Dates
First posted Feb 17, 2023 · updated Jul 25, 2023

Registry summary

Mortality following elective colorectal cancer surgery range between 2.5-6% and increase for the elderly and frail patient regardless of T-stage. Around 80% of the patients who present with a colon cancer and is in a condition where surgery is possible will be offered resection of the tumor. A part of the colon is always removed together with the lymph nodes in order to ensure that cancer cells are not left behind. The risk of lymph node metastasis is dependent on several histopathological characteristics of the tumor. The overall risk of lymph node metastases is less than 20 % in patients with early colon cancer. This indicates that the majority of patients with early colon cancer have no benefit of additional resection besides local tumor excision. The alternative to resecting a larger part of the bowel is to make more focused surgery only resecting a small part of the bowel part through a combination of laparoscopic and endoscopic techniques. This new organ sparing approach is called Combined Endoscopic Laparoscopic Surgery (CELS). The investigators aimed to examinate the hypothesis that organ preserving approach (CELS) provides superior quality of recovery in elderly frail patients with small colon cancers when compared with standard surgery in RCT.

Sites (3)

  • Copenhagen University Hospital - Herlev, Copenhagen, Herlev, Denmark
  • Hospital Soenderjylland, Aabenraa, Denmark
  • Zealand University Hospital, Køge, Denmark
Report a problem