What this means
Healthy people will take thinking tests and have brain scans to see how aging may change decision-making. This is a study that is still recruiting, so no results are available yet.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 18–60
- Where
- 1 site
The science
- Registered title
- Neural Bases of Decision-making in Healthy Individuals
- Trial ID
- NCT05774834 ↗
- Phase
- Not applicable
- Study type
- observational
- Conditions
- Healthy Volunteers
- What is tested
- No intervention
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
- Ages
- 18 Years to 60 Years
- Dates
- First posted Mar 20, 2023 · updated May 8, 2026
Registry summary
The goal of this single center non-interventional fMRI study is to assess the neural bases of decision-making and executive functioning in healthy individuals,and whether/how their responsiveness is modulated by ageing. The main questions it aims to answer are:
- are there specific neural correlates for ageing effects on executive functioning (particularly inhibitory control) and decision-making?
- Is there a relationship, at the behavioral and neural levels, between ageing-related changes in executive functioning and decision-making?
Healthy participants will be recruited for
- a behavioral assessment including multiple tests of decision-making and executive functioning/inhibitory control;
- a fMRI session to collect data concerning a) brain activity associated with decision-making and executive functioning, b) brain structural morphometriy (grey-matter volume/density), and c) brain structural connectivity (diffusion weighted imaging).
Results will provide an useful baseline for investigating alterations of decision-making and executive functioning, and of their neural bases, in pathological conditions.
Sites (1)
- Istituti Clinici Scientifici Maugeri SpA, Pavia, Ita, Italy