What this means
This is a plan to test whether frailty before hospital raises the risk of death in people 65 and under in intensive care. The study has not reported results yet, so it cannot yet show whether frailty matters.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 18–65
- Where
- 5 sites
The science
- Registered title
- Evaluation of the Clinical Frailty Scale (CFS) as a Risk Factor of Mortality in Adult Patients ≤65 Years of Age Admitted to Intensive Care for Septic Shock.
- Trial ID
- NCT05928767 ↗
- Phase
- Not applicable
- Study type
- observational
- Conditions
- Frailty, Septic Shock
- Sponsor
- Centre Hospitalier de Lens
- Ages
- 18 Years to 65 Years
- Dates
- First posted Jul 3, 2023 · updated Sep 28, 2026
Registry summary
The aim of the study is to demonstrate that "frail" patients, defined as having a CFS score greater than or equal to 5, and "severely" frail patients, defined as having a CFS score between [6-7] as defined by Bagshaw et al (14), constitute an independent risk factor (RF) for mortality.
In the same way, as an exploratory study, we will try to find out whether clinical frailty constitutes a risk factor for extending the length of hospital stay, the risk of short/medium-term readmission, as has already been demonstrated for patients admitted to intensive care from all causes (15), or for impaired quality of life.
The objective is to have a better understanding of the implications and outcomes associated with pre-hospital frailty in young critically ill patients.
This analysis will also help to clarify prognoses and contribute to better decision-making on the intensity and proportionality of care, as well as providing better information and helping to manage the expectations of patients and their families in terms of survival prognosis and subsequent quality of life.
Sites (5)
- Ch Germon Et Gauthier, Béthune, France
- CH Boulogne sur Mer, Boulogne-sur-Mer, France
- CHU de Dijon, Dijon, France
- CH de Lens, Lens, France
- CHU Lille, Lille, France