What this means
This is a trial that has not started yet, so no results exist. It will compare memory training with real stimulation against training with fake stimulation.
Plain-English summary written by an AI model from the registry listing.
- Status
- Opening soon
- Who can join
- Ages 65–85
- Where
- Not listed
The science
- Registered title
- Non-invasive Brain Stimulation and Strategic Memory Training
- Trial ID
- NCT05929872 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Cognitive Decline, Healthy Aging
- What is tested
- Non-invasive brain stimulation, Sham non-invasive brain stimulation
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
- Ages
- 65 Years to 85 Years
- Dates
- First posted Jul 3, 2023 · updated Jul 3, 2023
Registry summary
Physiological aging is often associated with memory function decline. Recently, the use of transcranial direct current stimulation (tDCS), a type of non-invasive brain stimulation, has been combined with adaptive working memory training interventions in healthy older adults, providing evidence for a significant improvement in memory functions. To the best of our knowledge, no study addressed the use of strategic memory training coupled with the use of tDCS in normal aging. Strategic memory trainings allow to improve participants' performance in the practiced task and to generalize the use of memory strategies to new materials. This Randomized Controlled Trial (RCT) aims to evaluate the effectiveness of a combined intervention associating strategic memory training with the use of tDCS. Healthy older adults and participants with subjective cognitive decline will be recruited and randomly assigned to the experimental group (strategic memory training + ACTIVE tDCS) or the control group (strategic memory training + SHAM tDCS). All participants will be evaluated on transfer and practiced tasks before (T0) and after (T1) the treatment and during follow-up visits, scheduled at 1 month (T2) and 3 months (T3) after the intervention.
