What this means
This trial plans to test a 16-week supervised exercise program in men with advanced prostate cancer. It has not reported results, so it does not yet show whether the program helps.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 18 and over
- Where
- 3 sites, including Massachusetts
The science
- Registered title
- Debunking the Frailty-sarcopenIa-ADT Axis in mEtastatic Prostate canceR With multiComponent Exercise: The FIERCE Trial
- Trial ID
- NCT06040125 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- PROSTATE CANCER, Metastatic Prostate Cancer, Metastatic Prostate Carcinoma
- What is tested
- Supervised Circuit Training
- Sponsor
- Dana-Farber Cancer Institute
- Ages
- 18 Years to no maximum
- Dates
- First posted Sep 15, 2023 · updated Sep 10, 2026
Registry summary
The purpose of this study is to determine whether a 16-week supervised, clinic-based circuit training intervention utilizing resistance and functional exercises and self-directed aerobic exercise will improve frailty and sarcopenic status and disease progression outcomes among pre-frail/frail metastatic prostate cancer patients receiving androgen deprivation therapy (ADT).
The names of the study intervention involved in this study is:
- Supervised circuit training (aerobic and resistance exercise regimen)
Sites (3)
- Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
- Brigham and Women's Hospital, Boston, Massachusetts, United States
- Dana-Farber Cancer Institute, Boston, Massachusetts, United States