What this means
Researchers plan to measure brain blood flow, brain activity, and balance in people of different ages. This is a study that has not reported results, so it cannot yet tell us how these things connect.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 21–95 · 102 adults: younger, middle-aged, and older
- Where
- 1 site, including Minnesota
The science
- Registered title
- Brain Vascular and Neural Function Linked to Balance Across the Adult Lifespan
- Trial ID
- NCT06127667 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Neurotypical, Cognitively Normal
- What is tested
- aerobic exercise
- Sponsor
- University of Minnesota
- Ages
- 21 Years to 95 Years
- Dates
- First posted Nov 13, 2023 · updated Mar 27, 2026
Registry summary
This is a single-arm, two-visit, non-randomized, cross sectional study identified as an intervention due to the use of a single bout of aerobic exercise to assess cerebrovascular function under the NIH rules. This study is not masked and its primary purpose is to develop a basic science understanding of the relationship between cerebrovascular health and balance control with aging. This study will involve 102 individuals classified as younger adults, middle-aged adults, and older adults who are neurotypical and cognitively normal. The primary outcome from a clinical trials perspective will be cerebrovascular response to a bout of aerobic exercise (i.e. change in cerebral blood flow with the performance of aerobic exercise on a recumbent stepper exercise machine). Non-interventional outcomes will be EEG measures of cortical activity and biomechanical kinetic and kinematic data recorded during standing balance reactions, as well as biological blood samples for genomic analysis.
Sites (1)
- University of Minnesota, Minneapolis, Minnesota, United States