What this means
Researchers will test two diets with different fats, each after a low fat diet. They want to see how fat types affect brain function. This is a trial that has not reported results yet, so it cannot tell us what the effects are.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 65–75
- Where
- 1 site, including Vermont
The science
- Registered title
- Fatty Acid Modulation of Brain Function in Older Adults
- Trial ID
- NCT06192407 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Aging
- What is tested
- High Oleic Acid Diet, High Palmitic Acid Diet
- Sponsor
- University of Vermont
- Ages
- 65 Years to 75 Years
- Dates
- First posted Jan 5, 2024 · updated Sep 17, 2025
Registry summary
In this crossover study, the investigtors will administer two experimental diets in a random order for one week, and each experimental diet will be preceded by a one-week, low fat control diet for a total four-week study period. The goal is to study how the fatty acid content of the diet affects brain functioning in healthy adults aged 65-75 years. One experimental diet will have a high palmitic acid (PA)/oleic acid (OA) ratio (HPA), typical of the North American diet. The other experimental diet will have a low PA/OA ratio (HOA), typical of the Mediterranean Diet. All allowed food and drink (except water) will be provided by the investigative team, and compliance will be enhanced by constant, intense dietary surveillance by a registered dietitian.
Sites (1)
- University of Vermont, Burlington, Vermont, United States