What this means
This is a plan for a study that has not started yet. It will compare exercise types in people with three conditions. No results are available, so it does not show which exercise works best.
Plain-English summary written by an AI model from the registry listing.
- Status
- Opening soon
- Who can join
- Ages 50–80
- Where
- Not listed
The science
- Registered title
- Effect of Exercise Type on Muscle Quality in Patients With OA, SARC and RA: an Explorative Study
- Trial ID
- NCT06480643 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Sarcopenia
- What is tested
- High load exercise type, Low load exercise type
- Sponsor
- Amsterdam UMC, location VUmc
- Ages
- 50 Years to 80 Years
- Dates
- First posted Jun 28, 2024 · updated Jun 28, 2024
Registry summary
C4M hypothesizes that patients with low muscle strength may respond differently to different types of exercise intervention, dependent on the underlying aetiology, i.e. impaired protein synthesis versus metabolic dysfunction and that this response is predictable based on the clinical diagnosis, i.e. rheumatoid arthritis (RA), osteoarthritis (OA) and Sarcopenia alone (SARC) and a number of clinical, blood based and muscle metabolic and architectural biomarkers. Understanding the underlying biochemical response of each patient group to the different type of exercise loading could help with the development of disease-specific training, making it more effective and more predictable on outcomes.