What this means
Researchers plan to study blood samples to see how lack of sleep may change the body. This is a planned study that has not reported results yet, so it does not show any effects yet.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 18–80
- Where
- 1 site
The science
- Registered title
- The Peripheral Blood Multi-Omics Study on Sleep Loss
- Trial ID
- NCT06492109 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Sleep Deprivation, Aging, Alzheimer Disease, Healthy Lifestyle, Cognitive Decline, Shift-work Disorder
- What is tested
- Sleep manipulation
- Sponsor
- First Affiliated Hospital of Zhejiang University
- Ages
- 18 Years to 80 Years
- Dates
- First posted Jul 9, 2024 · updated Jul 31, 2025
Registry summary
Sleep plays a role in cognitive processes such as memory processing, attention processing, and overall cognitive function. In recent years, the bidirectional relationship between sleep loss and aging, as well as related neurodegenerative diseases, has garnered widespread attention. Sleep disorders are a typical clinical manifestation of neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease and are closely related to the progression of these diseases. However, current research has yet to fully elucidate the physiological responses to sleep loss across different ages and cognitive levels, as well as the association and molecular basis between sleep loss, aging, and neurodegenerative diseases. This study aims to comprehensively characterize the transcriptional and metabolic changes in peripheral blood under sleep loss in populations of different ages and cognitive levels using multi-omics approaches and to preliminarily explore the role of sleep loss in aging and AD.
Sites (1)
- The First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang, China