What this means
Researchers plan to test whether soluble corn fiber changes how much calcium the gut takes in. The study has not started reporting results, so it cannot yet say whether fiber helps.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 60 and over · 30 older male Veterans
- Where
- 1 site, including California
The science
- Registered title
- Fiber and Calcium Absorption in Older Men
- Trial ID
- NCT06519877 ↗
- Phase
- PHASE 2
- Study type
- interventional
- Conditions
- Aging
- What is tested
- Soluble corn fiber
- Sponsor
- VA Office of Research and Development
- Ages
- 60 Years to no maximum
- Dates
- First posted Jul 25, 2024 · updated Feb 17, 2026
Registry summary
Osteoporotic fractures are a major but underrecognized problem in men. There is growing evidence that low dietary fiber intake is a modifiable risk factor for age-related bone loss in men. Preclinical and human studies in adolescents and postmenopausal women suggest that dietary fiber intake influences bone metabolism by modulating the gut microbiome to augment intestinal calcium absorption, but it is unclear through what molecular mechanism and whether dietary fiber has the same effects in older men. In this crossover intervention study, the investigators will enroll and follow 30 older male Veterans to evaluate the effects of soluble corn fiber on intestinal calcium absorption and explore the contribution of the gut microbiome.
Sites (1)
- San Francisco VA Medical Center, San Francisco, CA, San Francisco, California, United States