What this means
This is a plan to study muscles in active and inactive adults. It does not yet show whether exercise slows muscle aging.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 18–65
- Where
- 1 site
The science
- Registered title
- Skeletal Muscle Mitochondria in Ageing
- Trial ID
- NCT06539078 ↗
- Phase
- Not applicable
- Study type
- observational
- Conditions
- Aging
- What is tested
- Maximal exercise test, 3D Ultrasound, Dynamometry, Exercise test and occlusions, Exercise test in MRI, Muscle biopsy
- Sponsor
- VU University of Amsterdam
- Ages
- 18 Years to 65 Years
- Dates
- First posted Aug 6, 2024 · updated Aug 6, 2024
Registry summary
Healthy ageing is associated with the loss of muscle mass and physical function. As a result, older people are limited in their independence. The aging of muscles typically begins around the age of 30. From this age onward, muscle strength, muscle mass, and the maximum oxygen uptake of muscles decrease. The reasons for this are not entirely clear, but it seems to be partly related to how oxygen moves from our blood vessels to the muscles and how muscles burn energy. The precise role of age and physical fitness, as well as whether exercise can counteract the effects of ageing, is still unknown. Therefore, in this study, we aim to investigate the muscle function of both physically active and inactive young and middle-aged individuals. We hypothesise that endurance training can mitigate some of the effects of ageing.
Sites (1)
- Vrije Universiteit Amsterdam, Amsterdam, North Holland, Netherlands