What this means
This study will compare taking leucine after exercise with a meal versus between meals. It is a trial that is recruiting, so no results are available yet.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 65–75
- Where
- 1 site
The science
- Registered title
- Leucine Supplementation Strategies to Enhance Muscle Anabolic Responses in Older Age
- Trial ID
- NCT06567665 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Muscle Protein Synthesis
- What is tested
- Leucine
- Sponsor
- University of Nottingham
- Ages
- 65 Years to 75 Years
- Dates
- First posted Aug 23, 2024 · updated May 4, 2026
Registry summary
Sarcopenia describes the progressive decline of muscle mass and strength with advancing age and is associated with increased frailty and morbidity, however we do not currently have an effective treatment. Protein feeding and exercise is known to increase muscle mass, but aged muscle shows a lower response to these stimuli leading to muscle loss over time. We do know that ingesting leucine, a building block of protein, can overcome this reduced response to protein feeding and exercise leading to increased muscle mass in older people. However, we do not understand when the optimum time to ingest leucine is to maximise muscle mass after exercise in older people. In this study we will examine the effect of feeding leucine after exercise either with a meal or between meals.
Sites (1)
- University of Nottingham, Nottingham, Nottinghamshire, United Kingdom