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Does weight-loss surgery change biological age in people with obesity?

Recruiting · Nantes University Hospital

What this means

This is a plan to study people before and after weight-loss surgery. It has not reported any results yet, so it cannot yet show whether the surgery changes biological age.

Plain-English summary written by an AI model from the registry listing.

Status
Recruiting
Who can join
Ages 18–70
Where
1 site

Contacts and how to join ↗

The science

Registered title
Nantes Bariatric Surgery Cohort
Phase
Not applicable
Study type
interventional
Conditions
Obesity
What is tested
Nantes bariatric surgery cohort
Sponsor
Nantes University Hospital
Ages
18 Years to 70 Years
Dates
First posted Oct 3, 2024 · updated Apr 3, 2026

Registry summary

While current research suggests that inflammation of adipose tissue in obesity is linked to accelerated aging, it has yet to be determined in humans how this could enhance preventative and personalized medicine for obese individuals. The NBC study aims to investigate :

  • Whether bariatric surgery is associated with changes in biological age
  • If bariatric surgery alters adipocyte dysfunction, the microbiota and biological rhythms
  • Whether changes in adipocyte dysfunction, microbiota and biological rhythms are linked to changes in biological age.

To achieve this, establishing a biocollection before, during and after bariatric surgery will be crucial in addressing these questions

Sites (1)

  • Nantes University Hospital, Nantes, Loire-Atlantique, France
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