What this means
This is a plan to test whether a daily vitamin and mineral pill lowers biological age in middle-aged people. The study has not reported results, so it cannot yet show whether it works.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 40–60
- Where
- 2 sites
The science
- Registered title
- Daily Intake of Multivitamin & Mineral Supplementation Effects on Biological Age of Relatively Healthy Middle-aged Individuals
- Trial ID
- NCT06666660 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Relatively Healthy Volunteers
- What is tested
- Multivitamin/Mineral supplements, Placebo
- Sponsor
- National University of Singapore
- Ages
- 40 Years to 60 Years
- Dates
- First posted Oct 30, 2024 · updated Oct 30, 2024
Registry summary
Micronutrients, such as vitamins and minerals, are required to sustain fundamental physiological processes in individuals. As individuals age, the risk of having suboptimal levels of micronutrients increases due to several age-related changes affecting their digestion and assimilation processes. Suboptimal levels of micronutrients have been associated with increased risk of chronic diseases and accelerated ageing. Three years intake of a multivitamin and mineral supplement (MVM) improved global cognition, episodic memory and executive function in older adults. Furthermore, suboptimal micronutrient levels have been associated with a higher biological age, and diet and lifestyle interventions might lower the biological age measured by methylation clocks. Therefore, further evaluation is warranted to determine if MVM supplementation could improve the biological age and clinical outcomes in individuals with a higher biological age.
Sites (2)
- Healthy Longevity Translational Research Programme, Level 3, MD 11, 10 Medical Dr, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, Singapore
- Center for Healthy Longevity, Clinic L, Alexandra Hospital, 378 Alexandra Road, Singapore, Singapore, Singapore