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Does Alzheimer's change how people swallow, compared with healthy older adults

Recruiting · Vanderbilt University Medical Center

What this means

This study will compare swallowing and coughing tests in people with Alzheimer's and healthy adults. It is still recruiting, so no results are available yet.

Plain-English summary written by an AI model from the registry listing.

Status
Recruiting
Who can join
Ages 60 and over
Where
1 site, including Tennessee

Contacts and how to join ↗

The science

Registered title
Swallowing Impairments in Adults With and Without Alzheimer's Disease
Phase
Not applicable
Study type
observational
Conditions
Alzheimer Disease, Caregiver Burden, Healthy Aging, Dysphagia
Sponsor
Vanderbilt University Medical Center
Ages
60 Years to no maximum
Dates
First posted Nov 7, 2024 · updated May 8, 2026

Registry summary

This research study is investigating whether people with Alzheimer's disease (AD) experience more changes to swallowing than their healthy age-matched peers. The prevalence of swallowing impairments in moderate-severe AD is high (85-93%), yet little is known about how swallow function evolves throughout the disease course in people with AD. The overall objective of this study is to evaluate swallowing function in adults with and without Alzheimer's disease. The investigator will also be involving the primary caregivers of individuals with Alzheimer's that are enrolled in the study to better understand the impact of swallowing impairments on the primary caregivers of those with Alzheimer's Disease.

Healthy adults and individuals with Alzheimer's disease will:

  • undergo tests of cough and swallow function
  • undergo tests of grip and tongue strength
  • complete questionnaires

Caregivers of individuals with Alzheimer's disease will also complete questionnaires.

Sites (1)

  • Vanderbilt University Medical Center, Nashville, Tennessee, United States

More aging trials in these states

Tennessee

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