What this means
Researchers plan to compare 40 healthy adults over 55, half active for 30 years and half not. They want to see how exercise relates to muscles, metabolism, and immune cells.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 55 and over · 40 healthy adults over 55 (trial is recruiting, no results yet)
- Where
- 1 site
The science
- Registered title
- Sedentary or Exercised : Neuromuscular and Immunometabolic Observations and Retrospection
- Trial ID
- NCT06692543 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Aging
- What is tested
- Active population, Inactive population
- Sponsor
- Centre Hospitalier Universitaire de Nice
- Ages
- 55 Years to no maximum
- Dates
- First posted Nov 18, 2024 · updated May 22, 2026
Registry summary
The distinction between healthy and pathological ageing has given rise to the vitality capacity concept. Underlying the physiological aspect of ageing, vitality capacity is reflected in the neuromuscular function, metabolism, and immune and stress response. The three domains seem to deteriorate with age, except among individuals who have maintained physical activity throughout their lives. Furthermore, immune cells, particularly T lymphocytes, appear to play a key role in each dimension of vitality capacity, as well as in the mice ageing pathway. Investigators sought to determine the effect of lifelong physical activity on vitality capacity, and especially on T cell metabolism.
In this optic, fourty healthy participants over the age of 55 will be allocated to two groups: 20 who have maintained physical activity for the past 30 years, and 20 who have not. Each participant's vitality capacity will be deeply tested and compared to their physical activity background.
Sites (1)
- CHU de Nice, Nice, France