What this means
This study plans to look at blood from people with sepsis in intensive care. It will check whether certain genetic elements link to immune aging, death, and new infections.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 18 and over
- Where
- 1 site, including California
The science
- Registered title
- Role of Transposable Elements in Septic Immune Aging
- Trial ID
- NCT06809868 ↗
- Phase
- Not applicable
- Study type
- observational
- Conditions
- Sepsis, Sepsis and Septic Shock, Sepsis With Multiple Organ Dysfunction (MOD), Sepsis With Acute Organ Dysfunction, Sepsis, Severe, Sepsis at Intensive Care Unit, Sepsis, Severe Sepsis and Septic Shock, Sepsis, Septic Shock
- What is tested
- RNA and DNA Sequencing
- Sponsor
- University of California, San Francisco
- Ages
- 18 Years to no maximum
- Dates
- First posted Feb 5, 2025 · updated Jan 30, 2026
Registry summary
The goal of this observational study is to learn about how transposable element levels affect the patient outcomes in sepsis. The main questions it aims to answer is:
- Do transposable elements prematurely age the immune systems of patients with sepsis?
- Do transposable elements correlate with increased mortality in patients with sepsis in the ICU?
- Do transposable elements correlate with increased amount of secondary infections in patients with sepsis in the ICU?
Participants will have blood drawn from them but will not be subjected to additional interventions.
Sites (1)
- University of California, San Francisco, San Francisco, California, United States