What this means
Researchers plan to measure a body stress marker in fluid and blood from women and in sperm. They will compare it with IVF and pregnancy results. This study is still recruiting, so it cannot yet tell us what they found.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 18–43
- Where
- 1 site, including California
The science
- Registered title
- The ROAR Study: Reactive Oxygen Species and Reproduction
- Trial ID
- NCT06831019 ↗
- Phase
- Not applicable
- Study type
- observational
- Conditions
- Ovarian Aging, IVF Outcome, Oxidative Stress
- What is tested
- Oxidative stress markers
- Sponsor
- University of California, San Francisco
- Ages
- 18 Years to 43 Years
- Dates
- First posted Feb 17, 2025 · updated Feb 17, 2026
Registry summary
This is a prospective cohort study characterizing follicular fluid and serum levels of oxidative stress in women with various infertility diagnoses undergoing in vitro fertilization, and assessing the relationship of oxidative stress to oocyte competence as determined by embryo development outcomes. Furthermore, we will measure oxidative stress in sperm and correlate the overall oxidative stress within the couple with IVF and pregnancy outcomes of the resultant embryos.
Sites (1)
- University of California, San Francisco, San Francisco, California, United States