What this means
This study plans to test whether low-oxygen breathing and exercise, alone or together, help thinking and brain health. It has not started yet, so it cannot show whether either approach works.
Plain-English summary written by an AI model from the registry listing.
- Status
- Opening soon
- Who can join
- Ages 50–65 · Middle-aged adults aged 50 to 65
- Where
- Not listed
The science
- Registered title
- Investigating the Combined Effects of Intermittent Hypoxia and Exercise on Cognitive and Cerebral Function in Middle-Aged Adults
- Trial ID
- NCT06874387 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Cognitive Ability, General, Brain Health, Cerebral Oxygenation
- What is tested
- Hypoxia, intermittent, physical exercise, Sham (No Treatment) hypoxia
- Sponsor
- Ayoub Boulares
- Ages
- 50 Years to 65 Years
- Dates
- First posted Mar 13, 2025 · updated Mar 13, 2025
Registry summary
This study investigates whether intermittent hypoxia (IH) and physical activity (PA), either alone or in combination (simultaneously or sequentially), can improve cognitive function and brain health in middle-aged adults (50-65 years old). The hypothesis is that (1) each intervention alone (IHT or PA) provides cognitive benefits and (2) combining IHT with PA may yield additive or synergistic effects, particularly when administered simultaneously rather than sequentially. By comparing these distinct interventions, the study aims to determine which approach best preserves or enhances cognitive performance in middle-aged adults. Findings from this research may inform non-pharmacological strategies to promote healthy aging and reduce the risk of age-related cognitive decline.