What this means
This planned trial will compare protein supplements plus strength training against no extra intervention, for people taking weight-loss medicine. It has not started recruiting, so it does not yet show any results or effects.
Plain-English summary written by an AI model from the registry listing.
- Status
- Opening soon
- Who can join
- Ages 45 and over · 240 adults aged 45 and older with overweight or obesity, planned, not yet recruiting
- Where
- Not listed
The science
- Registered title
- Impact of Protein Supplementation and Resistance Training on Body Composition, Functional Parameters, Metabolic Adaptation, and Nitrogen Balance in Adults Aged 45 Years and Older With Overweight or Obesity Receiving Incretin-based Medications
- Trial ID
- NCT06950684 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Obesity, Overweight (BMI > 25), Weight Loss
- What is tested
- Whey Protein Supplement, Resistance Training Program
- Sponsor
- Assuta Medical Center
- Ages
- 45 Years to no maximum
- Dates
- First posted Apr 30, 2025 · updated Apr 30, 2025
Registry summary
This study aim to evaluate the effects of protein supplements and resistance training on body composition, functional parameters, metabolic adaptation, and nitrogen balance in adults (aged ≥45 years) with overweight/obesity receiving weekly Incretin-Based obesity management medication treatment for 6 months.
A parallel design, open-label, multicenter randomized controlled trial will be conducted among 240 patients (aged ≥45 years) initiating Incretin-Based obesity management medication. Participants will be recruited through obesity clinics at the Tel-Aviv Sourasky Medical Center and the Tel-Aviv Assuta Medical Center, obesity clinics of HMOs, and social media groups. They will be randomly assigned to one of two groups in a 1:1 ratio: protein supplements ('Easy Whey' 25 gr protein/day) plus weekly resistance training and no intervention. Data will be collected at baseline, 3, and 6 months, including demographics, medical status, body composition, functional parameters, resting metabolic rate, nitrogen balance, and physical activity performance.
All participants will be advised to follow an exercise regime, a reduced-calorie diet based on the principle of the Mediterranean eating pattern and be encouraged to follow a regular meeting schedule with a registered dietitian.