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New muscle test being studied for diagnosing sarcopenia in older hospital patients

Recruiting · Assistance Publique - Hôpitaux de Paris

What this means

Researchers plan to study a muscle signal test to find markers for sarcopenia, which is loss of muscle mass and strength. This is a planned study, and it has not reported any results yet.

Plain-English summary written by an AI model from the registry listing.

Status
Recruiting
Who can join
Ages 75 and over · 846 people aged 75 and over in hospitals
Where
11 sites

Contacts and how to join ↗

The science

Registered title
High-definition Surface Electromyography Markers for the Diagnosis and Monitoring of Sarcopenia
Phase
Not applicable
Study type
interventional
Conditions
Sarcopenia
What is tested
HD-sEMG, Quadriceps muscle ultrasound, IPAQ Physical Activity Questionnaire
Sponsor
Assistance Publique - Hôpitaux de Paris
Ages
75 Years to no maximum
Dates
First posted May 9, 2025 · updated Feb 13, 2026

Registry summary

Sarcopenia is a progressive and generalised skeletal muscle disorder involving the accelerated loss of muscle mass and function that is associated with increased adverse outcomes including falls, functional decline, frailty, and mortality. In this project, the high-definition surface electromyography technology (HD-sEMG) signals will be analysed to extract features/ markers for the diagnosis of sarcopenia. This is a multicentric, descriptive, cross-sectional, parallel group study to develop a new diagnostic method.

It is planned to include 846 people aged 75 years and over hospitalized in the acute geriatric or rehabilitation wards and suspected of sarcopenia (Score ≥4 on the SARC-F screening questionnaire). The inclusion duration will be 18 months and adding a 3-month patient follow-up. The total study duration will be 21 months. Patients will have their body composition using bioimpedancemetry and if possible by dual X-ray absorptiometry (DEXA). Muscular strength will be assessed by handgrip strength. Physical performance will be assessed. Additional data will be collected from their medical records.

Sites (11)

  • Hôpital Corentin Celton, APHP, Issy-les-Moulineaux, France
  • Hôpital Corentin Celton, APHP, Issy-les-Moulineaux, France
  • Hôpital Charles Foix, APHP, Ivry-sur-Seine, France
  • Hôpital Charles Foix, APHP, Ivry-sur-Seine, France
  • Hôpital Charles Foix, APHP, Ivry-sur-Seine, France
  • Unité d'Explorations fonctionnelles du sujet âgé - Hôpital Charles Foix, Ivry-sur-Seine, France
  • Hôpital Rothschild, APHP, Paris, France
  • Hôpital Rothschild, APHP, Paris, France
  • Hôpital Saint-Antoine, APHP, Paris, France
  • Hôpital Bichat, APHP, Paris, France
  • Hôpital Tenon, APHP, Paris, France
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