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Memory training study for people with mild memory problems is recruiting

Recruiting · Douglas Mental Health University Institute

What this means

This is a trial that is still signing up people, so no results exist yet. It will test whether a 3-month spatial memory program helps memory and the hippocampus, a brain area linked to memory.

Plain-English summary written by an AI model from the registry listing.

Status
Recruiting
Who can join
Ages 55 and over
Where
1 site

Contacts and how to join ↗

The science

Registered title
Spatial Memory Training and Cognitive Function
Phase
Not applicable
Study type
interventional
Conditions
Mild Cognitive Impairment
What is tested
SMIP, No intervention
Sponsor
Douglas Mental Health University Institute
Ages
55 Years to no maximum
Dates
First posted Jun 4, 2025 · updated Jul 23, 2025

Registry summary

Mild cognitive impairment (MCI) is often considered a transitional stage between normal aging and dementia, particularly Alzheimer's disease (AD). Patients with MCI have subjective memory complaints corroborated by standard neuropsychological tests but remain functionally autonomous. One of the first brain regions to show AD pathology is the hippocampus (HPC). Reduction in HPC volume is a strong predictor of AD dementia. Therefore, improvement or restoration of HPC structure and function is thus an attractive target for improvement in memory and AD prevention strategies. In the current study, the investigators propose to examine the effects of a 3-month long spatial memory program on spatial memory and the hippocampus in patients diagnosed with MCI. Neuropsychological tests are also administered before and after the training to assess the effects of the intervention on cognition. In our previous research, the investigators have shown that spatial memory intervention program (SMIP) improves cognition and hippocampal based spatial memory compared to controls.

Sites (1)

  • Douglas Mental Health University Institute, Verdun, Quebec, Canada
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