What this means
This study plans to compare kidney injury after surgery in frail and non-frail patients. It will also look at whether blood pressure during surgery explains part of that link.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 18 and over
- Where
- 1 site
The science
- Registered title
- The Relationship Between Preoperative Frailty and Postoperative AKI and the Mediating Effect of Intraoperative BP
- Trial ID
- NCT07030179 ↗
- Phase
- Not applicable
- Study type
- observational
- Conditions
- Postoperative Acute Kidney Injury, Frailty
- What is tested
- Frailty status
- Sponsor
- Lanyue Zhu
- Ages
- 18 Years to no maximum
- Dates
- First posted Jun 22, 2025 · updated Apr 2, 2026
Registry summary
The primary objectives of study is to compare the difference in the incidence of postoperative AKI between frail and non-frail patients. The secondary objectives of study was to compare the differences in intraoperative blood pressure fluctuations, the incidence and duration of intraoperative hypotension, postoperative extubation time, postoperative complications, length of hospital stay and hospitalization expenses between frail and non-frail patients, and use mediating effect analysis to examine the magnitude of the effect of intraoperative blood pressure on postoperative acute kidney injury caused by frailty.
Sites (1)
- Zhongda Hospital Southeast University, Nanjing, Jiangsu, China