What this means
This is a planned trial that has not reported results yet. It will compare usual arthritis care with and without resveratrol for three months.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 18 and over · 118 adults with moderate rheumatoid arthritis
- Where
- 1 site
The science
- Registered title
- Efficacy and Safety of Resveratrol in Patients With Rheumatoid Arthritis.
- Trial ID
- NCT07089381 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Rheumatic Arthritis, Rheumatoid Arthritis (RA) Prevention, Inflamation, Antioxidant, Anti Oxidative Stress, Anti Aging, C Reactive Protein, Methotrexate, Quality of Life Outcomes
- What is tested
- Resveratrol 1 gm., Methotrexate
- Sponsor
- Ain Shams University
- Ages
- 18 Years to no maximum
- Dates
- First posted Jul 28, 2025 · updated Jul 28, 2025
Registry summary
The aim of the current study is to evaluate the effects of resveratrol on the clinical outcome(s) of patients with moderate rheumatoid arthritis.
Objectives :
- To investigate the effects of Resveratrol on inflammation and oxidative stress by measuring:
- Serum Sirtuin 1(SIRT1)
- Serum Myeloperoxidase (MPO)
- Serum C-reactive protein (CRP)
- To investigate the effects of Resveratrol on disease activity by measuring the disease activity (DAS28 score).
- To investigate the effect of Resveratrol on improving the quality of life using the Health Assessment Questionnaire Disability index (HAQ-DI).
- To assess any adverse effects related to Resveratrol.
Patients:
Eligible patients (no=118) will be randomly assigned in a 1:1 ratio to one of two groups:
- Control group: 59 patients will receive the standard treatment for management of RA for 3 months.
- Resveratrol group: 59 patients will receive the standard treatment for management of RA in addition to Resveratrol 1 gm daily, (Organix Egypt) (given as one 1000 mg tablets once daily) for 3 months.
Sites (1)
- Department of Rheumatology at Ain Shams university hospital, Cairo, Egypt, Cairo, Egypt