Saturday, October 17, 2026 · Edition updated 6:00 AM ETSAT, OCT 17 · 6 AM ET editionNext edition in Next --:--:--

How aging affects leg muscle endurance during exercise with and without blood flow restriction

Opening soon · University of British Columbia

What this means

This trial plans to compare how many leg lifts younger and older adults can do at different weights. It will also look at how muscles use oxygen. The trial has not started and has no results yet.

Plain-English summary written by an AI model from the registry listing.

Status
Opening soon
Who can join
Ages 19 and over
Where
1 site

Contacts and how to join ↗

The science

Registered title
The Effects of Age on Muscle Endurance During Resistance Exercise With and Without Blood Flow Restriction
Phase
Not applicable
Study type
interventional
Conditions
Ageing, Muscle Fatigue Caused by Repetitive Muscle Exercise
What is tested
Knee extension exercise
Sponsor
University of British Columbia
Ages
19 Years to no maximum
Dates
First posted Jul 29, 2025 · updated Jul 29, 2025

Registry summary

The purpose of this study is to learn how aging affects muscle endurance during resistance exercise, and how oxygen delivery to the muscles plays a role in these changes. To answer this question, we are comparing how many repetitions of a leg exercise (knee extensions) younger and older adults can do at different exercise intensities. We will also look at how the muscles use oxygen during these exercises.

Participants will take part in 12 different exercise sessions. In each session, they will perform as many knee extensions as possible using different amounts of weight-consisting of 20%, 30%, 40%, 50%, 60% and 70% of the maximum weight they can lift one time. Each weight will be tested both with and without a cuff on the leg that temporarily reduces blood flow to the muscle.

Sites (1)

  • Chan Gunn Pavilion, Vancouver, British Columbia, Canada
Report a problem