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A trial is testing colon-delivered vitamin B2 on gut bacteria in older adults

Recruiting · dsm-firmenich Switzerland AG

What this means

This trial compares a special form of vitamin B2 that reaches the colon with regular vitamin B2 and a placebo. It has not reported results yet, so we cannot know what it found.

Plain-English summary written by an AI model from the registry listing.

Status
Recruiting
Who can join
Ages 50–70
Where
1 site

Contacts and how to join ↗

The science

Registered title
Colon-delivered Riboflavin and Gut Microbiota Composition
Phase
Not applicable
Study type
interventional
Conditions
Microbiome Dysbiosis, Gut Health
What is tested
Colon-delivered riboflavin, Conventional riboflavin, Microcrystalline Cellulose
Sponsor
dsm-firmenich Switzerland AG
Ages
50 Years to 70 Years
Dates
First posted Jul 30, 2025 · updated Mar 19, 2026

Registry summary

Recent studies suggest B-vitamins such as riboflavin to possess prebiotic-like effects. However, there is still a lack of understanding of the exact host health benefits vs. conventional systemically available vitamin forms. The present study explores the benefit of colon-delivered vitamin B2 vs. conventional vitamin B2 in comparison to placebo in an aging population on gut microbiota and metabolic activity as well as gut health.

Sites (1)

  • analyze & realize GmbH, Berlin, State of Berlin, Germany
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