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Can fasting and exercise slow aging in people over 65?

Recruiting · University of Copenhagen

What this means

A study is testing whether fasting, exercise, or both can slow aging over one year. It has not reported results yet, so it cannot yet show whether they work.

Plain-English summary written by an AI model from the registry listing.

Status
Recruiting
Who can join
Ages 20 and over · 240 people over 65 (trial not yet reported)
Where
1 site

Contacts and how to join ↗

The science

Registered title
FAXAGE: Fasting And Exercise To Slow Aging In Humans
Phase
Not applicable
Study type
interventional
Conditions
Aging, Healthy Aging, Aging Frailty
What is tested
Exercise - Strength + Cardio, Time-restricted feeding, Time-restricted feeding + Exercise
Sponsor
University of Copenhagen
Ages
20 Years to no maximum
Dates
First posted Oct 3, 2025 · updated Jan 28, 2026

Registry summary

FAXAge is a randomized controlled trial investigating the effects of fasting and exercise on human aging. 240 participants over the age of 65 will be divided into 4 groups - an exercise group, a fasting group, a combined exercise and fasting group and a control group. The intervention will last for one year, and tests of biomarkers of aging will be performed at baseline, after 3 months, 6 months and at the end of the intervention. A reference group of participants over the age of 20 equally distributed by age and sex will be used to train an algorithm for determination of biological age. The study will include both physical, molecular and digital biomarkers including DNA-methylation, VO2max, body composition and face- and voice-age. The main outcome of the project is DNA-methylation age at week 52. Secondary outcomes are the rest of the tested biomarkers at week 52. It is hypothesised that the intervention groups will have similar superior benefits after the 52 weeks of intervention.

Sites (1)

  • University of Copenhagen, Copenhagen, Copenhagen N, Denmark
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