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Can a supplement plus exercise help older adults' immunity and health?

Recruiting · University of Valencia

What this means

This is a trial that is still recruiting people, so no results are available yet. It will test whether a natural supplement plus exercise changes immunity, health, and stress in the body.

Plain-English summary written by an AI model from the registry listing.

Status
Recruiting
Who can join
Ages 65 and over
Where
1 site

Contacts and how to join ↗

The science

Registered title
Supplement and Exercise Effects on Stationary Immunity and Health in Older Adults
Phase
Not applicable
Study type
interventional
Conditions
Aging, Older Adults
What is tested
Group 1: Exercise + nutritional supplement (EXNS), Group 2: Exercise + placebo nutritional supplement (EXPlaNS)
Sponsor
University of Valencia
Ages
65 Years to no maximum
Dates
First posted Nov 26, 2025 · updated Dec 22, 2025

Registry summary

The goal of this clinical trial is to learn whether a natural-origin nutritional supplement, combined with a moderate-intensity functional exercise program, can improve seasonal immunity, perceived health, and oxidative stress in older adults. The study will also assess the safety of this combined intervention.

The main questions it aims to answer are:

  • Does the combination of supplementation and exercise enhance immune function during seasonal changes?
  • Does it reduce oxidative stress and improve perceived health and functional capacity?

Researchers will compare a supplement to a placebo. All participants will follow the same supervised functional exercise program.

Participants will:

  • Take a daily nutritional supplement for 6 months.
  • Attend two weekly functional exercise sessions (60 minutes each), including mobility, explosive strength, and coordination/agility training.
  • Complete three assessments (before, midway, and after the intervention) including blood tests, physical function evaluations, and quality of life questionnaires.

Sites (1)

  • Physical activity and Sport Science Faculty, Valencia, Valencia, Valencia, Valencia, Spain
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