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Can blood markers predict emergency room visits in frail older adults

Recruiting · University of Pisa

What this means

This is a planned study that will track older adults who need help with daily life. It aims to see whether certain blood and brain-vessel markers predict emergency visits over six months. No results have been posted, so it cannot yet show whether these markers work.

Plain-English summary written by an AI model from the registry listing.

Status
Recruiting
Who can join
Ages 65 and over
Where
1 site

Contacts and how to join ↗

The science

Registered title
Predictors of Emergency Department Use in Frail Patients
Phase
Not applicable
Study type
observational
Conditions
Alzheimer s Disease, Vascular Dementia, Frailty, Elderly, Emergency Department Visits, Autonomy
What is tested
Plasma phosphorylated Tau 181
Sponsor
University of Pisa
Ages
65 Years to no maximum
Dates
First posted Dec 2, 2025 · updated Dec 2, 2025

Registry summary

When admitted to the emergency department (ED), elderly non-autonomous patients show high risk of adverse health outcomes. The prompt identification of ED use risk factors in such population is hence needed. While cognitive impairment is a known clinical risk factor, biomarkers of most prevalent dementias have been scarcely investigated as possible ED use predictors. Within this context, this prospective study aims at exploring whether plasma phospho-tau181 and cerebrovascular burden can predict ED use at 6 months in elderly non-autonomous patients, irrespective of frailty.

Sites (1)

  • Azienda Ospedaliera Universitaria Pisana, Pisa, Pisa, Italy
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