What this means
This is a planned study that will track older adults who need help with daily life. It aims to see whether certain blood and brain-vessel markers predict emergency visits over six months. No results have been posted, so it cannot yet show whether these markers work.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 65 and over
- Where
- 1 site
The science
- Registered title
- Predictors of Emergency Department Use in Frail Patients
- Trial ID
- NCT07259499 ↗
- Phase
- Not applicable
- Study type
- observational
- Conditions
- Alzheimer s Disease, Vascular Dementia, Frailty, Elderly, Emergency Department Visits, Autonomy
- What is tested
- Plasma phosphorylated Tau 181
- Sponsor
- University of Pisa
- Ages
- 65 Years to no maximum
- Dates
- First posted Dec 2, 2025 · updated Dec 2, 2025
Registry summary
When admitted to the emergency department (ED), elderly non-autonomous patients show high risk of adverse health outcomes. The prompt identification of ED use risk factors in such population is hence needed. While cognitive impairment is a known clinical risk factor, biomarkers of most prevalent dementias have been scarcely investigated as possible ED use predictors. Within this context, this prospective study aims at exploring whether plasma phospho-tau181 and cerebrovascular burden can predict ED use at 6 months in elderly non-autonomous patients, irrespective of frailty.
Sites (1)
- Azienda Ospedaliera Universitaria Pisana, Pisa, Pisa, Italy
