What this means
Researchers plan to see if exercise helps children with leukemia keep or rebuild muscle during early treatment. The trial has not reported results yet, so it cannot show whether exercise works.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 5–17
- Where
- 1 site
The science
- Registered title
- Physical Activity and Exercise During Early Treatment Phases for Childhood Acute Lymphoblastic Leukaemia to Protect Against Muscle Loss and Improve Frailty Outcomes
- Trial ID
- NCT07325305 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Sarcopenia, Acute Lymphoblastic Leukemia
- What is tested
- Exercise
- Sponsor
- Murdoch Childrens Research Institute
- Ages
- 5 Years to 17 Years
- Dates
- First posted Jan 8, 2026 · updated Jul 6, 2026
Registry summary
This is a small trial testing out a new approach before doing a bigger study. Researchers are observing a group of children/adolescents (ages 5-17) with acute lymphoblastic leukemia (ALL) and testing a physical activity and exercise program on a group of them who after 5 weeks of treatment show signs of weakness or frailty.
Kids who are NOT losing muscle aren't part of the exercise trial - they're just monitored over time to see how they do.
The goal:
To see if an exercise program helps kids who are getting weaker from acute lymphoblastic leukemia treatment build back/maintain their strength, compared to kids who don't do the extra intervention. The study will also look at if this way of measuring muscle weakness works well for kids with cancer.
Sites (1)
- Royal Children's Hospital, Melbourne, Victoria, Australia