What this means
This trial will test a daily drink with a probiotic called LcS against a plain milk drink for eight weeks. It has not reported results, so we do not yet know if it helps.
Plain-English summary written by an AI model from the registry listing.
- Status
- Recruiting
- Who can join
- Ages 40–60
- Where
- 1 site
The science
- Registered title
- Skin Inflammation in (Peri)Menopause: A Probiotic Intervention Proof of Concept Trial
- Trial ID
- NCT07341087 ↗
- Phase
- Not applicable
- Study type
- interventional
- Conditions
- Skin Inflammation, Immunosenescence, Inflammation, Skin Health, Eczema, Rosacea, Acne, Menopause
- What is tested
- Lactobacillus casei Shirota (LcS) Probiotic Drink, Skimmed Milk Control Drink
- Sponsor
- King's College London
- Ages
- 40 Years to 60 Years
- Dates
- First posted Jan 14, 2026 · updated May 8, 2026
Registry summary
This study will explore whether a daily probiotic drink containing Lactobacillus casei Shirota (LcS) can help improve immune function and reduce inflammation in women going through the menopausal transition. Hormonal changes during this stage of life can affect the immune system, gut health, and skin, sometimes leading to increased inflammation or conditions such as eczema, acne or rosacea.
Participants will consume either a low-sugar LcS probiotic drink or a skimmed milk control drink every day for eight weeks. The study will assess markers of immune ageing, inflammation, skin health, wellbeing, and hormone levels. The results will help determine whether a safe, non-hormonal probiotic approach may support immune and skin health during the menopausal transition.
Sites (1)
- Metabolic Research Unit, 4th Floor (Corridor A), Franklin-Wilkins Building, KCL., London, London, United Kingdom